Pyoderma Gangrenosum Treatment

Pyoderma gangrenosum treatment papules (blisters) start as small red bumps, maturing into a skin ulcer (open sore) with extreme risk of infection.

What is Pyoderma Gangrenosum Treatment?

Pyoderma gangrenosum is rare disease prompting skin inflammation and ulcers on the upper layer of the skin. Medications, environmental elements and health issues are culprits for this ailment. Mild to moderate ulcers generally heal in a few days. Infection is the catalyst leading to severe consequences and the need for immediate medical attention.

The condition is treatable, although it may leave scars on the skin and recurrences are common. The root cause of pyoderma gangrenosum is uncertain. Research and studies have the disorder linked to genetics and autoimmune diseases, indicating a higher risk for individuals with these medical and family histories.

  • Crohn’s disease
  • Inflammatory bowel disease
  • Rheumatoid arthritis
  • Ulcerative colitis

Health incidents instigating the formation of skin ulcers are skin traumas, cuts or puncture wounds and surgical incisions. Sometimes, medications affect the body’s immune system triggering the condition as a side effect. The ulcer appears on the lower extremities of the body with some episodes appearing on the surface of the hands, forearms and the face.

Unfortunately, there is no prevention of this disease, but it can be controlled with the avoidance of skin trauma. There are two forms of pyoderma gangrenosum treatment, each recognizable by the appearance and location of the ulcers.

  • Traditional – purple colored borders – lower extremities
  • Atypical – shallow fluid-filled blisters – on the surface of hands, outside forearms or face.

What Causes Pyoderma Gangrenosum Treatment?

The exact cause of pyoderma gangrenosum is unknown - skin traumas will provoke new eruptions. Determining the direct root is difficult because tests don’t always confirm a diagnosis of the disorder. Medical studies and practices purpose comparable ulcer syndromes (underlying conditions) in determining the best defensive treatments based on effectiveness.

Specific health factors increase the possibility of skin complications like pyoderma gangrenosum.

  • Depression
  • Infections
  • Loss of mobility
  • Uncontrolled pain

The condition can happen at any age, yet individuals with existing health disorders or 40 years of age are at higher risks. Individuals being treated with immune ailments, or vulnerable to genetic diseases need to manage damages and control injuries to the skin.

  • The disease is not contagious and less likely to spread to other parts of the body.

Industry experts still do not fully understand the reasons for this disorder. Continued immune and inflammation initiatives aligned with tradition risk factors do play a role in successful treatment. For some patients, early detection can make a difference in preventing specific complications. Today the prognosis of people living with the condition has improved.

Treatment along with individual life changes are managing chronic conditions affecting skin injuries. Pharmaceutical innovations, improving drug safety have optimized potency, inhibiting advanced infections and initiating faster recovery.

Symptoms of Pyoderma Gangrenosum Treatment

The beginning symptoms of pyoderma gangrenosum are visible red bumps on the skin – sometimes confused with a spider bite. Over the next few days, the bump develops into an open sore on the surface of the skin. If you notice changes in the bump – contact the doctor. Like all disorders, the early treatments have significant health benefits.

Accompanying signs may begin slowly, increasing in acuteness. If the ulcers multiply, they can ultimately form a single large abscess, escalating the symptoms.

  • Body weakens
  • Joint pains
  • Pain

Because skin trauma activates pyoderma gangrenosum, precautions are necessary when considering surgical treatments to heal and close the ulcer. One procedure to close the open sore is skin grafting. Cuts to the skin can worsen existing ulcers and timely new ones.

How to Treat Pyoderma Gangrenosum Treatment

The primary focus for healing the ulcer is to reduce the inflammation and control the level of pain for the patient. In some cases, the length of recovery depends on the size and depth of the ulcer – demanding weeks or months to heal the sore. Your doctor may request an overnight stay at the hospital or a specialized wound treatment unit.

Wound specialists are comprised of several wound disciplines, treating acute and chronic injuries, surgical and systemic wounds (open sores). They work together, assessing and reporting a patient’s response to medications or changes to the condition.

  • Medical technicians
  • Nurses
  • Physicians
  • Therapists

Primary physicians coordinate the communications, directing needed therapy or other health measures including surgery or dermatology treatments. Care options help to diminish and ease the symptoms through recovery. Daily cleansing for pyoderma gangrenosum is part of the medical care routine for open wounds. Once the medicine is administered to the skin, it is covered with a dressing and wrapped.

Medical procedures consider individuals being treated for systemic conditions. Your doctor will require regular visits to monitor the effects of treatment.

Drugs prescribed for healing the ulcer include topicals, injections or oral measures.

  • Corticosteroids in high doses are the primary drug for treating this disorder.
  • For some incidents, immune system drugs are used to limit the dosage of corticosteroids.
  • Pain medications may be necessary when cleaning and dressing the open sore.


Corticosteroids are known to have side effects when taken for long durations and in large dosage. As the ulcer heals and fades, your doctor will reduce the dosage. Following the care directions of the doctor is critical to healing, because some medications suppress the immune system. The situation can inhibit the body’s defense response to infection.

If the wound does not show any improvement after a month, your doctor may recommend a specialist for further evaluation and treatment. Your contribution is learning more about the disorder, and how best to care and protect your skin from future injury.

Storage and Handling

Drugs are used to restore and sustain our health, left unmonitored even the purest form can cause harm.

  • Keep all medicines out of reach of children, elderly adults, and animals.
  • Store medications in a cool, dry place away from direct heat or light.
  • Discard outdated or unused portions properly.

Frequently asked questions

1. Is pyoderma gangrenosum treatment contagious?

Yes. Contact with an infected person or contaminated clothing or objects carries the live virus.

2. Do I need to see a doctor?

Yes, if the bumps develop quickly followed with pain – it’s time to see the doctor. Left untreated the condition will worsen.

3. Can pyoderma gangrenosum treatment spread to other body parts?

Yes. The virus causes a severe itch to the skin. If you scratch an existing area and unintentionally touch another body area, the virus will spread.

4. How can I avoid future episodes of pyoderma gangrenosum treatment?

Trauma can cause recurrence of this disorder. In some cases, such as surgery or other medical treatments, avoidance may not be possible. Talk with your doctor and discuss the past events.

5. What types of medications are used to treat pyoderma gangrenosum treatment?

The course of treatment considers the skin’s situation, and the second action treats the cause given the individual’s health status. Medications used include steroids, immunosuppressants, and immunoglobulin.

6. Does the form of treatment affect my chances of successfully terminating pyoderma gangrenosum treatment?

Treatments for the disorder include topical, injections and oral drugs. Your doctor will diagnosis which form works best for the situation. If the condition does not improve with the first round of treatment, the doctor may opt to use a combination of medicines to increase the prescription potency. New and specialized treatments can help aid in the healing without the assistance of frequent medications.

7. How common is pyoderma gangrenosum treatment?

The condition is uncommon. And reports show more than 50% of affected patients have some level of systemic disease. Recurring episodes appear in 30% of individuals after a trauma or injury to the skin.